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AZ31-induced cytotoxicity is prevented by PLGA in human fibroblasts and <t>osteoblasts.</t> Cell viability was measured by MTT assay in human ( a ) fibroblasts and ( b ) osteoblasts non-exposed (CTRL) or exposed to the different indicated agents. Exposure was performed for 72 h. Data report the means of three separate experiments performed in triplicate, and error bars represent the standard deviation (SD) of the mean. ** p < 0.01 and *** p < 0.001 significantly different from control unexposed cells. # p < 0.05 and ## p < 0.01 significantly different from AZ31-exposed cells. ^ p < 0.05 significantly different from ketorolac-exposed cells.
Primary Human Osteoblasts, supplied by PromoCell, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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PromoCell osteoblasts
AZ31-induced cytotoxicity is prevented by PLGA in human fibroblasts and <t>osteoblasts.</t> Cell viability was measured by MTT assay in human ( a ) fibroblasts and ( b ) osteoblasts non-exposed (CTRL) or exposed to the different indicated agents. Exposure was performed for 72 h. Data report the means of three separate experiments performed in triplicate, and error bars represent the standard deviation (SD) of the mean. ** p < 0.01 and *** p < 0.001 significantly different from control unexposed cells. # p < 0.05 and ## p < 0.01 significantly different from AZ31-exposed cells. ^ p < 0.05 significantly different from ketorolac-exposed cells.
Osteoblasts, supplied by PromoCell, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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AZ31-induced cytotoxicity is prevented by PLGA in human fibroblasts and <t>osteoblasts.</t> Cell viability was measured by MTT assay in human ( a ) fibroblasts and ( b ) osteoblasts non-exposed (CTRL) or exposed to the different indicated agents. Exposure was performed for 72 h. Data report the means of three separate experiments performed in triplicate, and error bars represent the standard deviation (SD) of the mean. ** p < 0.01 and *** p < 0.001 significantly different from control unexposed cells. # p < 0.05 and ## p < 0.01 significantly different from AZ31-exposed cells. ^ p < 0.05 significantly different from ketorolac-exposed cells.
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AZ31-induced cytotoxicity is prevented by PLGA in human fibroblasts and <t>osteoblasts.</t> Cell viability was measured by MTT assay in human ( a ) fibroblasts and ( b ) osteoblasts non-exposed (CTRL) or exposed to the different indicated agents. Exposure was performed for 72 h. Data report the means of three separate experiments performed in triplicate, and error bars represent the standard deviation (SD) of the mean. ** p < 0.01 and *** p < 0.001 significantly different from control unexposed cells. # p < 0.05 and ## p < 0.01 significantly different from AZ31-exposed cells. ^ p < 0.05 significantly different from ketorolac-exposed cells.
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PromoCell trabecular bone tissue
AZ31-induced cytotoxicity is prevented by PLGA in human fibroblasts and <t>osteoblasts.</t> Cell viability was measured by MTT assay in human ( a ) fibroblasts and ( b ) osteoblasts non-exposed (CTRL) or exposed to the different indicated agents. Exposure was performed for 72 h. Data report the means of three separate experiments performed in triplicate, and error bars represent the standard deviation (SD) of the mean. ** p < 0.01 and *** p < 0.001 significantly different from control unexposed cells. # p < 0.05 and ## p < 0.01 significantly different from AZ31-exposed cells. ^ p < 0.05 significantly different from ketorolac-exposed cells.
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Innoprot Inc human primary osteoblasts p10971
AZ31-induced cytotoxicity is prevented by PLGA in human fibroblasts and <t>osteoblasts.</t> Cell viability was measured by MTT assay in human ( a ) fibroblasts and ( b ) osteoblasts non-exposed (CTRL) or exposed to the different indicated agents. Exposure was performed for 72 h. Data report the means of three separate experiments performed in triplicate, and error bars represent the standard deviation (SD) of the mean. ** p < 0.01 and *** p < 0.001 significantly different from control unexposed cells. # p < 0.05 and ## p < 0.01 significantly different from AZ31-exposed cells. ^ p < 0.05 significantly different from ketorolac-exposed cells.
Human Primary Osteoblasts P10971, supplied by Innoprot Inc, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cell Applications Inc human osteoblasts osteoarthritis
AZ31-induced cytotoxicity is prevented by PLGA in human fibroblasts and <t>osteoblasts.</t> Cell viability was measured by MTT assay in human ( a ) fibroblasts and ( b ) osteoblasts non-exposed (CTRL) or exposed to the different indicated agents. Exposure was performed for 72 h. Data report the means of three separate experiments performed in triplicate, and error bars represent the standard deviation (SD) of the mean. ** p < 0.01 and *** p < 0.001 significantly different from control unexposed cells. # p < 0.05 and ## p < 0.01 significantly different from AZ31-exposed cells. ^ p < 0.05 significantly different from ketorolac-exposed cells.
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AZ31-induced cytotoxicity is prevented by PLGA in human fibroblasts and <t>osteoblasts.</t> Cell viability was measured by MTT assay in human ( a ) fibroblasts and ( b ) osteoblasts non-exposed (CTRL) or exposed to the different indicated agents. Exposure was performed for 72 h. Data report the means of three separate experiments performed in triplicate, and error bars represent the standard deviation (SD) of the mean. ** p < 0.01 and *** p < 0.001 significantly different from control unexposed cells. # p < 0.05 and ## p < 0.01 significantly different from AZ31-exposed cells. ^ p < 0.05 significantly different from ketorolac-exposed cells.
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iXCells Biotechnologies lot no 200211
AZ31-induced cytotoxicity is prevented by PLGA in human fibroblasts and <t>osteoblasts.</t> Cell viability was measured by MTT assay in human ( a ) fibroblasts and ( b ) osteoblasts non-exposed (CTRL) or exposed to the different indicated agents. Exposure was performed for 72 h. Data report the means of three separate experiments performed in triplicate, and error bars represent the standard deviation (SD) of the mean. ** p < 0.01 and *** p < 0.001 significantly different from control unexposed cells. # p < 0.05 and ## p < 0.01 significantly different from AZ31-exposed cells. ^ p < 0.05 significantly different from ketorolac-exposed cells.
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PromoCell human hip
AZ31-induced cytotoxicity is prevented by PLGA in human fibroblasts and <t>osteoblasts.</t> Cell viability was measured by MTT assay in human ( a ) fibroblasts and ( b ) osteoblasts non-exposed (CTRL) or exposed to the different indicated agents. Exposure was performed for 72 h. Data report the means of three separate experiments performed in triplicate, and error bars represent the standard deviation (SD) of the mean. ** p < 0.01 and *** p < 0.001 significantly different from control unexposed cells. # p < 0.05 and ## p < 0.01 significantly different from AZ31-exposed cells. ^ p < 0.05 significantly different from ketorolac-exposed cells.
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PromoCell primary osteoblasts
AZ31-induced cytotoxicity is prevented by PLGA in human fibroblasts and <t>osteoblasts.</t> Cell viability was measured by MTT assay in human ( a ) fibroblasts and ( b ) osteoblasts non-exposed (CTRL) or exposed to the different indicated agents. Exposure was performed for 72 h. Data report the means of three separate experiments performed in triplicate, and error bars represent the standard deviation (SD) of the mean. ** p < 0.01 and *** p < 0.001 significantly different from control unexposed cells. # p < 0.05 and ## p < 0.01 significantly different from AZ31-exposed cells. ^ p < 0.05 significantly different from ketorolac-exposed cells.
Primary Osteoblasts, supplied by PromoCell, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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AZ31-induced cytotoxicity is prevented by PLGA in human fibroblasts and osteoblasts. Cell viability was measured by MTT assay in human ( a ) fibroblasts and ( b ) osteoblasts non-exposed (CTRL) or exposed to the different indicated agents. Exposure was performed for 72 h. Data report the means of three separate experiments performed in triplicate, and error bars represent the standard deviation (SD) of the mean. ** p < 0.01 and *** p < 0.001 significantly different from control unexposed cells. # p < 0.05 and ## p < 0.01 significantly different from AZ31-exposed cells. ^ p < 0.05 significantly different from ketorolac-exposed cells.

Journal: Polymers

Article Title: Ketorolac Loaded Poly(lactic-co-glycolic acid) Coating of AZ31 in the Treatment of Bone Fracture Pain

doi: 10.3390/polym15102246

Figure Lengend Snippet: AZ31-induced cytotoxicity is prevented by PLGA in human fibroblasts and osteoblasts. Cell viability was measured by MTT assay in human ( a ) fibroblasts and ( b ) osteoblasts non-exposed (CTRL) or exposed to the different indicated agents. Exposure was performed for 72 h. Data report the means of three separate experiments performed in triplicate, and error bars represent the standard deviation (SD) of the mean. ** p < 0.01 and *** p < 0.001 significantly different from control unexposed cells. # p < 0.05 and ## p < 0.01 significantly different from AZ31-exposed cells. ^ p < 0.05 significantly different from ketorolac-exposed cells.

Article Snippet: Primary human osteoblasts were purchased from PromoCell (Heidelberg, Germany) and cultured in DMEM (Invitrogen, Paisley, UK) supplemented with 10% fetal calf serum (FCS, Invitrogen, Paisley, UK), antimycotic and antibiotics (Invitrogen, Paisley, UK) [ ].

Techniques: MTT Assay, Standard Deviation, Control